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Office of Research > Resources for Researchers > Compliance & Security > Human Research Protection Program > Resources and Guidance > HRPP Toolkit

HRPP Toolkit

The HRPP Toolkit is a comprehensive set of documents that include standard operating procedures, worksheets, checklists, templates, and manuals.

Investigators are required to read and follow HRP-103 – INVESTIGATOR MANUAL for conducting research with human participants.

The Toolkit contains a large catalog of SOPs (HRP-001 through HRP-096), Worksheets (HRP-301 series), Checklists (HRP-410 series), Templates (HRP-502, HRP-503, HRP-593 series), and the Investigator Manual. For the most current list of files, see the full toolkit at the legacy IRB site. A complete document index migration is pending.

SOPs are organized by business process (e.g. pre-review, review, post-review) rather than by topic. They cross reference worksheets and checklists, so information is not duplicated. While the majority of SOPs are for HRPP/IRB staff and IRB members, there are two SOPs for researchers: HRP-090 – SOP – Informed Consent Process for Research and HRP-091 – SOP – Written Documentation of Consent.

The full SOP catalog (HRP-001 through HRP-096) is hosted on SharePoint. See the legacy SOPs page for current links to each document.

Worksheets are used by HRPP/IRB staff for regulatory decision making during the review process that does not need to be formally documented. The full Worksheet catalog (HRP-301 through HRP-352) is hosted on SharePoint. See the legacy SOPs page for current links to each worksheet.

Checklists are used by HRPP/IRB staff for regulatory decision making that must be documented and retained in the study record within PERA. The full Checklist catalog (HRP-410 through HRP-418) is hosted on SharePoint. See the legacy SOPs page for current links to each checklist.

Protocol Templates

Investigators must use one of the templates for writing protocols submitted to the IRB. To know which documents you should submit, first review “Getting Started” and read HRP-103 – Investigator Manual.

  • HRP-503a – TEMPLATE – Protocol (Non-Exempt)
  • HRP-503c – TEMPLATE – Protocol (Exempt)
  • HRP-503b – TEMPLATE – Protocol (Human Research Determination)
  • HRP-503e – TEMPLATE – Protocol (External IRB Site Supplement)

Consent / Assent / Permission Templates

  • HRP-502a – Consent Form
  • HRP-502b – Information Sheet for Exempt Research
  • HRP-502d – Assent Form

Additional appendices (HRP-593 Appendix A–O) cover specific populations and situations and are available in the SharePoint Protocol & Consent Templates library. See the legacy SOPs page for the full appendix list.

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