New method for interpreting cryo-EM maps makes it easier to determine protein structures
A new algorithm makes interpreting the results of cryo-electron microscopy maps easier and more accurate, helping researchers to determine protein structures and potentially create drugs that block their functions.
Cryo-electron microscopy, or cryo-EM, uses electron beams to obtain 3-D images of biomolecular structures. The use of this technique has skyrocketed in recent years due to technolgical advancements, but as cryo-EM gains steam in the field, additional tools are needed to interpret the images it outputs.